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KMID : 1130320080510111228
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Korean Journal of Pediatrics
2008 Volume.51 No. 11 p.1228 ~ p.1231
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A case of vancomycin-induced drug hypersensitivity syndrome
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Min Kyung-Sun
Choi Woo-Yeon
Song Eun-Song
Han Dong-Kyun
Cho Young-Kuk
Ma Jae-Sook
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Abstract
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Drug hypersensitivity syndrome (DHS) has rarely been reported in association with vancomycin treatment. Here, we describe an 1 1 -year-old girl who developed fever and a maculopapular rash on day 1 8 of intravenous vancomycin for treatment of infective endocarditis. The patient presented with fever, a maculopapular skin rash, hepatitis, and acute renal failure caused by vancomycin-induced DHS. The symptoms resolved in less than 2 4 h after withdrawal of vancomycin and treatment with corticosteroids. We present this case of DHS associated with vancomycin.
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KEYWORD
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Drug hypersensitivity syndrome, Vancomycin
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